Al Depope

Publications

Journal and conference papers, preprints and selected talks. An up-to-date record is also on ORCID. Joint first authorship is marked with an asterisk.

Journal & conference papers

  1. 2026

    Joint modeling of whole-genome sequencing data for human height via approximate message passing

    A. Depope, J. Bajzik, M. Mondelli, M. R. Robinson

    JournalCell Genomics 6(5), 101162

    We develop gVAMP, an approximate message passing paradigm that fine-maps whole-genome sequence variants and gene burden scores conditional on all other measured DNA variation genome-wide, and show that the genetic architecture of height inferred from WGS data differs systematically from the one inferred from imputed SNPs.

  2. 2026

    Joint Variable Selection in Proteomics Survival Models

    J. Bajzik*, A. Depope*, Y. Zolfimoselo, A. Sharipov, A. Lesayova, H. Klein, A. Richmond, S. Vernardis, A. Grauslys, S. Andrejev, A. Zelezniak, M. Ralser, R. E. Marioni, M. Mondelli, M. R. Robinson

    WorkshopICLR Workshop on Machine Learning for Genomics Explorations

    A scalable Bayesian framework for joint variable selection in time-to-event models. Applied to the UK Biobank Pharma Proteomics Project, it improves onset prediction by 26–33% relative to penalised Cox and baseline deep-learning approaches.

  3. 2024

    Inference of Genetic Effects via Approximate Message Passing

    A. Depope, M. Mondelli, M. R. Robinson

    ConferenceIEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)

Interdisciplinary collaborations

Statistical analysis and data visualisation for the Textile Recycling Group at TU Wien.

  1. 2026

    DES formulation for recycling synthetic fibre textile waste containing elastane

    N. Depope, A. Depope, VM. Archodoulaki, A. Dabrowska, B. Lendl, A. Mautner, W. Ipsmiller, A. Bartl

    JournalWaste Management

  2. 2025

    Deep eutectic solvent as a solution for polyester/cotton textile recycling

    N. Depope, A. Depope, VM. Archodoulaki, W. Ipsmiller, A. Bartl

    JournalWaste Management 208, 115177

Preprints & work in progress

  1. 2026

    Joint Variable Selection for Omic Biomarkers in Time-to-Event Data

    J. Bajzik*, A. Depope*, et al.

    PreprintbioRxiv

  2. WIP

    Incorporating summary statistics into the VAMP framework

    A. Depope*, J. Bajzik*, M. Mondelli, M. R. Robinson

    sgVAMP adapts gVAMP to the summary-statistics setting and extends it to a multi-cohort model that jointly estimates shared and population-specific signals across ancestries.

  3. WIP

    Epigenome-wide association studies using approximate message passing

    J. Bajzik*, A. Depope, D. L. McCartney, M. J. Bauer, R. E. Marioni, M. Mondelli, M. R. Robinson

    gVAMPomi applied to the Generation Scotland study finds 92 trait-associated CpG probes conditional on all other probes, against 37 for the baseline MCMC approach.

  4. WIP

    Detection of age-specific genetic effects for age-at-onset complex traits

    S. E. Ojavee*, A. Depope*

    An extension of the time-to-event BayesW model to two and three epochs, with Gibbs updates derived for interaction and epoch-specific parameters.

Selected talks

  1. 2024

    Joint modelling of whole genome sequence data for human height

    Oral7th International Conference of Quantitative Genetics (ICQG)

  2. 2024

    Inference of Genetic Effects via Approximate Message Passing

    OralIEEE ICASSP 2024, Seoul

  3. 2024

    Light-speed whole genome association testing and prediction

    Best student presentation52nd European Mathematical Genetics Meeting, Vienna